challenges of genetic screening of in vitro fertilized human embryos using current technologies

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Challenges of Genetic Screening of In Vitro Fertilized Human Embryos Using Current Technologies

Human is usually sub-fertile in comparison to other mammals; in other words, reproduction process of other mammals is more effective than human. Chromosomal anomalies of early embryos are the major reason for the low fecundity of human per cycle. Most of embryos with major genetic defects may be implanted and it can be followed with stopping of early development and early embryo loss with no ta...

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Non-Invasive Assessment of Viability in Human Embryos Fertilized in Vitro

Human reproduction is a relatively inefficient process and therefore the number of infertile couples is high. Assisted reproductive technologies (ART) have facilitated the birth of over five million children worldwide. ART, however, superimposes its own relative inefficiency on the preexisting inefficiency of normal reproduction. The efficiency (expressed as pregnancy rate) is generally not mor...

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Release of sICAM-1 in Oocytes and In Vitro Fertilized Human Embryos

BACKGROUND During the last years, several studies have reported the significant relationship between the production of soluble HLA-G molecules (sHLA-G) by 48-72 hours early embryos and an increased implantation rate in IVF protocols. As consequence, the detection of HLA-G modulation was suggested as a marker to identify the best embryos to be transferred. On the opposite, no suitable markers ar...

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Comparative stepwise pattern of reactive oxygen species production during in vitro development of fertilized and nuclear transferred goat embryos

Objective A unique feature of embryo metabolism is production of reactive oxygen species (ROS). It is well established that during in vitro culture, ROS levels increase over normal ranges observed for embryos developed in vivo. This study evaluates and compares the stepwise pattern of ROS production during in vitro development of reconstructed goat embryos produced by zona-free method of somati...

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the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation

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عنوان ژورنال:
journal of reproduction and infertility

جلد ۱۷، شماره ۳، صفحات ۱۳۷-۱۳۸

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